Creatinine Clearance

Creatinine clearance

In pediatrics, it is generally corrected to a body surface area of 1.73 m2 (standard body surface area of an adult).

Collection Time (hr)
Urine Volume (mL)
Urine Creatinine (mg/dL)
Plasma Creatinine (mg/dL)
For correction for BSA
Weight (kg)		kg	lbs
Height (cm)		cm	in

CrCl (mL/min)	=
Corrected CrCl (mL/min/1.73*m²)	=

The formula for the calculation is as below. The BSA here is calculated from the height and weight with the formula of DuBois and DuBois.

CrCl =	U_Cr * U_Vol

	P_Cr * T_min

Corrected CrCl = CrCl *	1.73

	BSA

Reference range in our laboratory of an "uncorrected" creatinine clearance for an adult male is 90-139 mL/minute, and for an adult female is 80-125 mL/minute. Many medications must be adjusted for renal impairment when the CrCl falls below 50 mL/min.