Hyposphatemia Treatment
There are a variety of different formulations of phosphate available, both in enteral and parenteral form. The route of administration depends on the speed and availability of that route. Of the parenteral formulations, both sodium and potassium phosphate are available. I usually use the potassium preparation, as most ICU patients are deficient in both potassium and phosphate. In addition, I almost always add KPO4 to the dialysis fluid in CVVHDF. If the patient is severely hypophosphatemic, then intravenous replenishment at 6mg/kg/hour is administered until the PO4 level is above 2mg/dl.
Preparation |
Phosphate Content |
Sodium |
Potassium |
Oral preparation |
|||
Skim cow's milk |
1 g/L |
28 meq/L |
38 meq/L |
Neutra-Phos |
250 mg/packet |
7.1 meq/packet |
7.1 meq/packet |
Phospho-Soda |
150 mg/mL |
4.8 meq/mL |
0 |
Neutra-Phos K |
250 mg/capsule |
0 |
14.25 meq/capsule |
K-Phos Original |
150 mg/capsule |
0 |
3.65 meq/capsule |
K-Phos Neutral |
250 mg/tablet |
13 meq/tablet |
1.1 meq/tablet |
Intravenous preparations | |||
Neutral sodium potassium PO4 |
1.1 mmol/mL |
0.2 meq/mL |
0.02 meq/mL |
Neutral sodium PO4 |
0.09 mmol/mL |
0.2 meq/mL |
0 |
Sodium PO4 |
3.0 mmol/mL |
4.0 meq/mL |
0 |
Potassium PO4 |
3.0 mmol/mL |
0 |
4.4 meq/mL |
Fosfato Monopotasico (10 ml=1'3 gr de fosfato) | 1 mmol/mL | 1 mmol/mL |